HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-(Octane-1-sulfonyl)3-[4-(2-piperidin-yl-ethoxy)phenyl]-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-(Octane-1-sulfonyl) 3-[4-(2-piperidin-yl-ethoxy)phenyl]-propionic acid ethyl ester | HCID 10961872 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(Octane-1-sulfonyl)3-[4-(2-piperidin-yl-ethoxy)phenyl]-propionic acid | HCID 21267975 | — |
Reaction Steps
2-(Octane-1-sulfonyl)-3-[4-(2-piperidin-yl-ethoxy)-phenyl]-propionic acid was prepared according to the general method as outlined in example 9. Starting from 2-(octane-1-sulfonyl)-3-[4-(2-piperidin-yl-ethoxy)-phenyl]-propionic acid ethyl ester (8.9 g, 18 mmol), ethanol (25 mL) and 10 N sodium hydroxide (25 mL). Yield 6.0 g (72%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06197791B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-c26eadf22f0c4d24ba380927ec6945a5 |
| Source note | uspto-grants-2001_03 |