HCID 54032112, compound → HCID 53828855, compound

HRID 1531057Notes

Reaction equation

HRID 1531057 reaction equation
C([O:3][C:4](=[O:27])[C:5]([S:16]([C:19]1[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=1)(=[O:18])=[O:17])([CH3:15])[CH2:6][CH:7]=[CH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)C>CO.[OH-].[Na+]>[CH3:26][O:25][C:22]1[CH:21]=[CH:20][C:19]([S:16]([C:5]([CH3:15])([CH2:6][CH:7]=[CH:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:4]([OH:27])=[O:3])(=[O:18])=[O:17])=[CH:24][CH:23]=1

Participants

4

Reactant 1

HCID 54032112HCID 54032112, compound

Product 1

HCID 53828855HCID 53828855, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

2-(4-Methoxy-benzenesulfonyl)-2-methyl-5-phenyl-pent-4-enoic acid was prepared starting from 2-(4-methoxy-benzenesulfonyl)-2-methyl-5-phenyl-pent-4-enoic acid ethyl ester (3.0 g, 11 mmol) dissolved in methanol (50 ml) and 10 N NaOH (30 ml). The resulting reaction mixture was worked up as outlined in Example 9. Yield 1.9 g, 68%; yellowish oil; MS: 361 (M+H)+.

Workup

  1. customThe resulting reaction mixture

Sources & evidence

ORD record
ord-1009273a5ddd4c26999ae566dcb59e0c
Source dataset
uspto-grants-2001_03
Patent number
US06197791B1

Reaction notes

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