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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1531223Generated: October 31, 2026

1-(4-Fluorophenyl)-2-methylpropan-1-ol → 1-(4-Fluorophenyl)-2-methylpropan-1-one

https://huagongshe.com/reaction/1531223

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Fluorophenyl)-2-methylpropan-1-olHCID 10419564—
ReactantJones' reagentHCID 131709961—
SolventAcetoneHCID 180—
Product1-(4-Fluorophenyl)-2-methylpropan-1-oneHCID 2782829—

Reaction Steps

To a solution of 1-(4-Fluoro-phenyl)-2-methyl-propan-1-ol (1.6 g) in acetone (10 mL) at 0° C. is added Jones reagent (20 mL) with stirring. After 10 minutes excess Jones reagent is destroyed by addition of isopropyl alcohol. Diethyl ether is added followed by anhydrous magnesium and the mixture is filtered and evaporated to give the product, a yellow oil (1.2 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06197803B1
Source datasetuspto-grants-2001_03
ORD IDord-1523c6805ea64c1fbec7e9061d62db9b
Source noteuspto-grants-2001_03