3,5-Diiodosalicylaldehyde → HCID 178449922, compound

HRID 1531251Notes

Reaction equation

HRID 1531251 reaction equation
[I:1][C:2]1[C:3]([OH:11])=[C:4]([CH:7]=[C:8]([I:10])[CH:9]=1)[CH:5]=O.[C:12]([NH:16][OH:17])([CH3:15])([CH3:14])[CH3:13]>>[I:1][C:2]1[C:3]([OH:11])=[C:4]([CH:5]=[N+:16]([C:12]([CH3:15])([CH3:14])[CH3:13])[O-:17])[CH:7]=[C:8]([I:10])[CH:9]=1

Participants

3

Reactant 2

HCID 758293,5-DiiodosalicylaldehydeHCID 98586N-tert-butylhydroxylamine

Product 1

HCID 178449922HCID 178449922, compound

Procedure

The title compound was prepared according to the procedure described in Example 1 using 3,5-diiodo-2-hydroxybenzaldehyde and N-tert-butylhydroxylamine. The title compound was isolated in 73.8% yield as a yellow crystalline solid, m.p. 164.1° C. (Rf=0.38 on a silica gel plate using 7:3 hexanes/EtOAc as an eluant)

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-cceea4864dc94950923980c4cfee9103
Source dataset
uspto-grants-2001_03
Patent number
US06197826B1

Reaction notes

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