Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 178427593 | HCID 178427593 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | D-Arg(Tos)-Gly-OBn | HCID 178427563 | — |
Reaction Steps
A 1 g portion of Boc-(D)-Arg(Tos)-Gly-OBn (1.74 mmol) was dissolved in 10 mL of CH2Cl2, cooled to 0° C. and treated with 10 mL of TFA. The solution was stirred at 0° C. for 3 h. Solvent and excess TFA were evaporated thoroughly to give the title compound as an oil which was used directly in Example 10.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06197748B1 |
|---|
| Source dataset | uspto-grants-2001_03 |
|---|
| ORD ID | ord-a98fa9a0318a433eb2491526c60c9b8b |
|---|
| Source note | uspto-grants-2001_03 |
|---|
