HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indan-5-amine → 2-Bromo-N-indan-5-yl-5-nitro-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indan-5-amine | HCID 90496 | — |
| Reactant | 4''-Trifluoromethyl-biphenyl-2-carboxylic acid (2-benzenesulfonylamino-indan-5-yl)-amide | HCID 9893362 | — |
| Reactant | 2-Bromo-5-nitrobenzoyl chloride | HCID 11471072 | — |
| Product | 2-Bromo-N-indan-5-yl-5-nitro-benzamide | HCID 21253366 | — |
Reaction Steps
2-Bromo-N-indan-5-yl-5-nitro-benzamide is prepared similarly to the title E compound of Example 1 using the title A compound, 2-bromo-5-nitrobenzoyl chloride (1.07 g, 4.06 mmol) and 5-aminoindan (0.54 g, 4.06 mmol). 1H NMR (DMSO-d6, 300 MHz): δ 10.52 (1H, s), 8.34 (1H, d), 8.21 (1H, dd), 8.03 (1H, d), 7.60 (1H, s), 7.38 (1H, d), 7.19 (1H, d), 2.85 (4H, m), 2.02 (2H, m).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06197798B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-a935927ef9414c679508a4e87a2ff010 |
| Source note | uspto-grants-2001_03 |