HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 86756489, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Acetylene | HCID 6326 | — |
| Reactant | Tert-butylcarbamate | HCID 21252905 | — |
| Reactant | HCID 86756490 | HCID 86756490 | — |
| Product | HCID 86756489 | HCID 86756489 | — |
Reaction Steps
Methyl 2-{[4′-methoxy-(1,1′-biphenyl)-4-yl]-sulfonyl}-amino-6-(4N-phenylpiperazin-1N-yl)-hex-4-ynoate: N-Phenyl-1,4-piperazine (478 mg, 2.95 mmol) is coupled with paraformaldehyde (96 mg, 3.21 mmol wrt. monomer) and free acetylene 38e (1.0 g, 2.68 mmol) as described for compound 31a to give the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06197770B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-dfa06f1b686e475dbfdfca9378c5a4c9 |
| Source note | uspto-grants-2001_03 |