反应详情

The procedure of Example 1 was repeated except the following. The same reactor as used in Example 1 was charged with 13.5 g (0.067 mole) of a γ-(4-pyridyl)butyric acid hydrochloride with a purity of at least 99%, 27.0 g of water and 0.67 g of 5% Pd/C [0.25% by weight in terms of Pd based on the γ-(4-pyridyl)butyric acid hydrochloride]. The reaction was conducted at 80° C. for 4.5 hours. A γ-(4-piperidyl)butyric acid hydrochloride was produced in a yield of 97%.