HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → 4-Piperazinyl-2,6-bis-hydroxymethyl pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | Calcium Chloride | HCID 5284359 | — |
| Reactant | Diethyl-4-piperazinyl-2,6-pyridinedicarboxylate | HCID 85702736 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-Piperazinyl-2,6-bis-hydroxymethyl pyridine | HCID 21257329 | — |
Reaction Steps
Diethyl-4-piperazinyl-2,6-pyridinedicarboxylate is dissolved in THF and treated with NaBH4 and CaCl2 as per the procedure of Example 51 to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06197965B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-c0bae1602a0740e8b1c0f097bb6ca3a8 |
| Source note | uspto-grants-2001_03 |