Acetic Acid → HCID 21250080, compound

HRID 1531686Notes

Reaction equation

HRID 1531686 reaction equation
C([O:3][C:4]([C:6]1[CH:19]=[N:18][C:17]2[C:8](=[CH:9][CH:10]=[C:11]3[C:16]=2[N:15]=[CH:14][CH:13]([N+:20]([O-:22])=[O:21])[C:12]3=[O:23])[CH:7]=1)=[O:5])C.[OH-].[Na+].C(O)(=O)C>O>[C:4]([C:6]1[CH:19]=[N:18][C:17]2[C:8](=[CH:9][CH:10]=[C:11]3[C:16]=2[N:15]=[CH:14][CH:13]([N+:20]([O-:22])=[O:21])[C:12]3=[O:23])[CH:7]=1)([OH:5])=[O:3]

Participants

5

Reactant 3

HCID 176Acetic AcidHCID 14798Sodium HydroxideHCID 21250121HCID 21250121, compound

Product 1

HCID 21250080HCID 21250080, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 8-ethoxycarbonyl-3-nitro-4-oxo-3,4-dihydro-1,10-phenanthroline (0.55 g) and 2M sodium hydroxide solution (5 ml) was stirred at reflux for 2 hours. The hot suspension was neutralised with glacial acetic acid, cooled and diluted with water. The mixture was filtered and washed with water to give 8-carboxy-3-nitro-4-oxo-3,4-dihydro-1,10-phenanthroline in 98% yield.

Workup

  1. temperatureat reflux for 2 hours
  2. temperaturecooled
  3. filtrationThe mixture was filtered
  4. washwashed with water

Sources & evidence

ORD record
ord-7a0fb500f1614744a4df8e0c07d7c8e8
Source dataset
uspto-grants-2001_03
Patent number
US06200974B1

Reaction notes

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