Benzenesulfonyl chloride → HCID 136048899, compound

HRID 1531735Notes

Reaction equation

HRID 1531735 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([CH2:12][C:13]1[CH:20]=[CH:19][C:16]([C:17]#[N:18])=[CH:15][CH:14]=1)[NH:6][C:5]2=[O:21].[C:22]1([S:28](Cl)(=[O:30])=[O:29])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1.CN(C1C=CC=CN=1)C>N1C=CC=CC=1>[C:22]1([S:28]([NH:1][C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][CH:11]=2)[N:8]=[C:7]([CH2:12][C:13]2[CH:20]=[CH:19][C:16]([C:17]#[N:18])=[CH:15][CH:14]=2)[NH:6][C:5]3=[O:21])(=[O:30])=[O:29])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

5

Reactant 3

HCID 7369Benzenesulfonyl chlorideHCID 218852-DimethylaminopyridineHCID 135738535HCID 135738535, compound

Product 1

HCID 136048899HCID 136048899, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Prepared analogously to Example 1e from 4-[(6-amino-4-oxo-3,4-dihydro-quinazolin-2-yl)-methyl]-benzonitrile, benzenesulphonic acid chloride and dimethylaminopyridine in pyridine.

Sources & evidence

ORD record
ord-a64e6a0e748a4ffc9121d2619e82dba5
Source dataset
uspto-grants-2001_03
Patent number
US06200976B1

Reaction notes

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