HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 4-{[7-(2-Methyl-phenyl)-4-methyl-quinolin-2-yl]-amino}-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Tolylboric acid | HCID 13862916 | — |
| Reactant | 4-[(7-Bromo-4-methyl-quinolin-2-yl)-amino]-benzonitrile | HCID 21250371 | — |
| Catalyst | Tetrakis(triphenylphosphine)palladium | HCID 11979704 | — |
| Solvent | Toluene water | HCID 22272177 | — |
| Product | 4-{[7-(2-Methyl-phenyl)-4-methyl-quinolin-2-yl]-amino}-benzonitrile | HCID 21250381 | — |
Reaction Steps
Prepared analogously to Example 27e from 4-[(7-bromo-4-methyl-quinolin-2-yl)-amino]-benzonitrile, 2-methylphenylboric acid, tetrakis-(triphenylphosphine)-palladium (0) and sodium carbonate in toluene/water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06200976B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-22012316c63b4a83a3ffa8671bdfff37 |
| Source note | uspto-grants-2001_03 |