HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piconol → 3-(Pyrazin-2-yl)-6-(pyrid-2-yl)methyloxy-1,2,4-triazolo[3,4-a]phthalazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piconol | HCID 11474 | — |
| Reactant | 6-Chloro-3-(pyrazin-2-yl)-1,2,4-triazolo[3,4-a]phthalazine | HCID 18361841 | — |
| Product | 3-(Pyrazin-2-yl)-6-(pyrid-2-yl)methyloxy-1,2,4-triazolo[3,4-a]phthalazine | HCID 18361829 | — |
Reaction Steps
The title-compound was prepared from 6-chloro-3-(pyrazin-2-yl)-1,2,4-triazolo[3,4-a]phthalazine and 2-pyridylcarbinol using the procedure given for Example 98, 1H NMR (360 MHz, CDCl3) δ 5.77 (2H, s, CH2), 7.40 (1H, t, J=6.6 Hz, Ar—H), 7.71 (1H, d, J=7.8 Hz, Ar—H), 7.95-8.00 (2H, m, 2 of Ar—H), 8.08 (1H, t, J=7.6 Hz, Ar—H), 8.40 (1H, d, J=8.0 Hz, Ar—H), 8.70 (2H, m, 2 of Ar—H), 8.78 (1H, m, Ar—H), 8.88 (1H, s, Ar—H), 9.58 (1H, s, Ar—H); MS (ES30) m/e 356 [MH]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06200975B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-d89ecdd53bf2441591ce997d1d416216 |
| Source note | uspto-grants-2001_03 |