HCID 70239023, compound → HCID 70243273, compound

Participants

Reaction Steps

Boron tribromide (800 ml of 1N solution in dichloromethane) was added to a stirred solution of the compound of Example 98 (106 mg). The resulting white precipitate was stirred at room temperature for 2 hours. The reaction was quenched with methanolic ammonium hydroxide (1:1 v/v) and evaporated to dryness in vacuo. The residue was purified by column chromatography over silica gel (dichloromethane:methanol:ammonium hydroxide; 84:14:2) to afford the title compound, 36.5 mg.

Provenance & Evidence