Lithium hydroxide, monohydrate → HCID 21251123, compound

Participants

Reaction Steps

To a solution of 0.40 g (0.860 mmol) of the product of Example 18 in 9.0 mL of THF-MeOH (1:1) was added 0.072 g (1.72 mmol) of lithium hydroxide monohydrate. The reaction mix was heated to reflux for 18 h and then concentrated in vacuo. The residue was washed with THF and filtered. The filtrate was concentrated in vacuo to provide 0.388 g (100%) of the desired product as a white foam. Electrospray Mass Spec: 483 (M+H).

Provenance & Evidence