HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Bis(bromomethyl)benzoic acid ethyl ester → 3-[[3-Bromomethyl-5-[ethoxycarbonyl]phenyl]methoxy]-5-[2-methoxyethoxy]benzoic acid, methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Bis(bromomethyl)benzoic acid ethyl ester | HCID 15440343 | — |
| Reactant | Methyl 3-hydroxy-5-(2-methoxyethoxy)benzoate | HCID 131722431 | — |
| Product | 3-[[3-Bromomethyl-5-[ethoxycarbonyl]phenyl]methoxy]-5-[2-methoxyethoxy]benzoic acid, methyl ester | HCID 131722432 | — |
Reaction Steps
The subtitle compound was prepared from the product of step (iii) (1.5 g) and 3,5-bis(bromomethyl)benzoic acid ethyl ester (4.9g) by the method of example 11 step (i). Purification was by chromatography eluting with 30% ethyl acetate in isohexane. Yield 1.6 g. Used directly in the next step
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06200981B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-caf9639edc494774985cc43a69adad29 |
| Source note | uspto-grants-2001_03 |