HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-bromobutyrate → 4-[3-[[Ethoxycarbonyl]methoxy]-5-[hydroxymethyl]phenyloxy]butanoic acid, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-bromobutyrate | HCID 76300 | — |
| Reactant | 2-[3-Hydroxy-5-[hydroxymethyl]phenyloxy]acetic acid, ethyl ester | HCID 121006484 | — |
| Product | 4-[3-[[Ethoxycarbonyl]methoxy]-5-[hydroxymethyl]phenyloxy]butanoic acid, ethyl ester | HCID 131722438 | — |
Reaction Steps
The subtitle compound was prepared from the product of step (i) (1.6 g) and ethyl 4-bromobutyrate (1.38 g) by the method of example 21 step (ii). Purified by chromatography eluting with 30% ethyl acetate in toluene. Yield 0.43 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06200981B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-a0d89c52314241909e52af354b09be58 |
| Source note | uspto-grants-2001_03 |