N-(5-ethoxycarbonylmethyl-4,6-dimethylindolin-7-yl)-2,2-dimethylpropanamide → N-(5-ethoxycarbonylmethyl-4,6-dimethylindol-7-yl)-2,2-dimethylpropanamide

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Reaction Steps

N-(5-ethoxycarbonylmethyl-4,6-dimethylindolin-7-yl)-2,2-dimethyl-propanamide (1.0 g) was dissolved in xylene (75 ml), and 10% Pd—C. (250 mg) was added, which was followed by refluxing for 1 hr. Pd—C. was filtered off and xylene was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: benzene—CHCl3) to give 0.9 g of N-(5-ethoxycarbonylmethyl-4,6-dimethylindol-7-yl)-2,2-dimethylpropanamide.

Provenance & Evidence