HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N-(2-(4-hydroxyphenyl)ethyl)carbamate → 4-(2-t-Butoxycarbonylaminoethyl)phenoxymethyl-(3-benzyloxypropyl)phosphinic acid, n-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N-(2-(4-hydroxyphenyl)ethyl)carbamate | HCID 11831452 | — |
| Reactant | 3-Benzyloxypropyl-(4-chlorobenzenesulfonyloxymethyl)phosphinic acid, n-butyl ester | HCID 86752195 | — |
| Product | 4-(2-t-Butoxycarbonylaminoethyl)phenoxymethyl-(3-benzyloxypropyl)phosphinic acid, n-butyl ester | HCID 86752194 | — |
Reaction Steps
The title compound was prepared from 3-benzyloxypropyl-(4-chlorobenzenesulfonyloxymethyl)phosphinic acid, n-butyl ester and 2-(4-hydroxyphenyl)ethylcarbamic acid, t-butyl ester according to the procedure described in Procedure 24. The crude product was purified by chromatography, eluting with dichloromethane containing 3% methanol, to give an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05726165 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-d7fbc646e6f24341bd3baed08edf1bc8 |
| Source note | uspto-grants-1998_03 |