HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 2800279, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Fluoro-3-nitrobenzotrifluoride | HCID 67778 | — |
| Reactant | 3-Hydroxy-5-chloropyridine | HCID 582305 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 2800279 | HCID 2800279 | 96.7% |
Reaction Steps
Using the method of Example 21.2, 4-fluoro-3-nitrobenzotrifluoride (7.4 g) and 3-chloro-5-hydroxypyridine (4.59 g) were heated with potassium carbonate (5.4 g) in DMF at 80° C. for 1 h, then 60° overnight. Workup gave the title compound (10.9 g) as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06200995B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-c726de1016bf46fa8aafc36fb968e7de |
| Source note | uspto-grants-2001_03 |