HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1532016Generated: October 29, 2026
Potassium Carbonate → HCID 21251108, compound
https://huagongshe.com/reaction/1532016
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Fluoro-5-nitrobenzotrifluoride | HCID 94954 | — |
| Reactant | 3-Hydroxy-5-chloropyridine | HCID 582305 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21251108 | HCID 21251108 | 110.2% |
Reaction Steps
Using the method of Example 21.2, 2-fluoro-5-nitrobenzotrifluoride (5.0 g) and 3-chloro-5-hydroxypyridine (3.1 g) were combined with potassium carbonate (5.4 g) in DMF and heated overnight at 60° C. Workup gave the title compound (8.4 g) as a crude yellow solid which was used directly in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06200995B1 |
|---|
| Source dataset | uspto-grants-2001_03 |
|---|
| ORD ID | ord-1026dbfefe3d4d12af93e07001ba95ea |
|---|
| Source note | uspto-grants-2001_03 |
|---|
