HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formamide → HCID 88094878, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formamide | HCID 713 | — |
| Reactant | 3,4,5-Trimethoxybenzaldehyde | HCID 6858 | — |
| Reactant | p-Toluenesulfinic acid | HCID 10818 | — |
| Reactant | Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1S)- | HCID 18462 | — |
| Product | HCID 88094878 | HCID 88094878 | — |
Reaction Steps
A mixture of Example 1A (22.3 g, 0.15 mol), 3,4,5-trimethoxybenzaldehyde (35.32 g, 0.18 mol), and camphorsulfonic acid (3.48 g, 15 mmol) in formamide (40 mL) was stirred vigorously at 65° C. for 16 hours, cooled to room temperature, and filtered. The resulting solid was washed several times with methanol and dried to provide 13.4 g of the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06201001B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-fee6d5f6466449bd98a7a7894ad8e269 |
| Source note | uspto-grants-2001_03 |