Formamide → HCID 21250821, compound

HRID 1532059Notes

Reaction equation

HRID 1532059 reaction equation
S(O)(O)(=O)=O.[NH2:6][C:7]1[N:8]=[C:9]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[O:21][CH2:22][CH2:23][CH2:24][CH3:25])[NH:10][C:11](=[O:14])[C:12]=1[NH2:13].[CH:26](N)=O>>[CH2:22]([O:21][C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=1[C:9]1[N:8]=[C:7]2[C:12](=[N:13][CH:26]=[N:6]2)[C:11](=[O:14])[N:10]=1)[CH2:23][CH2:24][CH3:25]

Participants

3

Reactant 2

HCID 713FormamideHCID 136364571HCID 136364571, compound

Product 1

HCID 21250821HCID 21250821, compound

Procedure

In a similar manner to Example 1 reaction of 4,5-diamino-2-(2-butoxyphenyl)pyrimidin-6-one sulphate (1.5 g) with formamide (5 ml) afforded the title compound, 0.65 g, m.p. 247°-248° C., (recrystallised from ethanol).

Workup

  1. customafforded
  2. customthe title compound, 0.65 g, m.p. 247°-248° C., (recrystallised from ethanol)

Sources & evidence

ORD record
ord-e68bd1bc9cea4bbc9c2a9d60a15aa4d8
Source dataset
uspto-grants-2001_03
Patent number
US06200980B1

Reaction notes

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