(6-Methoxypyridin-3-yl)boronic acid → 4-(6-Methoxy-pyridin-3-yl)-1H-indole-2-carboxylic acid {1-[2-(3-hydroxy-8-aza-bicyclo[3.2.1]oct-8-yl)-ethyl]-piperidin-4-yl}-amide
Reaction equation
[CH3:31][O:32][c:33]1[cH:34][cH:35][c:36]([B:39]([OH:40])[OH:41])[cH:37][n:38]1.[OH:1][CH:2]1[CH2:3][CH:4]2[CH2:5][CH2:6][CH:7]([CH2:8]1)[N:9]2[CH2:10][CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([NH:18][C:19](=[O:20])[c:21]2[nH:22][c:23]3[cH:24][cH:25][cH:26][c:27]([Br:30])[c:28]3[cH:29]2)[CH2:16][CH2:17]1>>[OH:1][CH:2]1[CH2:3][CH:4]2[CH2:5][CH2:6][CH:7]([CH2:8]1)[N:9]2[CH2:10][CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([NH:18][C:19](=[O:20])[c:21]2[nH:22][c:23]3[cH:24][cH:25][cH:26][c:27](-[c:36]4[cH:35][cH:34][c:33]([O:32][CH3:31])[n:38][cH:37]4)[c:28]3[cH:29]2)[CH2:16][CH2:17]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-a613f00831104cb38458f5e77ab50d91
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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