Formamide → HCID 21250709, compound

HRID 1532060Notes

Reaction equation

HRID 1532060 reaction equation
S(O)(O)(=O)=O.[NH2:6][C:7]1[N:8]=[C:9]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[O:21][CH2:22][CH:23]([CH3:25])[CH3:24])[NH:10][C:11](=[O:14])[C:12]=1[NH2:13].[CH:26](N)=O>>[CH2:22]([O:21][C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=1[C:9]1[N:8]=[C:7]2[C:12](=[N:13][CH:26]=[N:6]2)[C:11](=[O:14])[N:10]=1)[CH:23]([CH3:25])[CH3:24]

Participants

3

Reactant 2

HCID 713FormamideHCID 136364572HCID 136364572, compound

Product 1

HCID 21250709HCID 21250709, compound

Procedure

In a similar manner to Example 1 reaction of 4,5-diamino-2-(2-isobutoxyphenyl)pyrimidin-6-one sulphate (1.4 g) with formamide (5 ml) afforded the title compound, 0.24 g, m.p. 272°-273° C., (recrystallised from ethanol).

Workup

  1. customafforded
  2. customthe title compound, 0.24 g, m.p. 272°-273° C., (recrystallised from ethanol)

Sources & evidence

ORD record
ord-af5799da37da4417bd6ebcea9f1e7c8e
Source dataset
uspto-grants-2001_03
Patent number
US06200980B1

Reaction notes

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