HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 2-Hydroxy-4-methylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Benzoic acid, 2-hydroxy-4-methyl-, methyl ester | HCID 78400 | — |
| Reactant | 4-Methyl-2-propoxybenzamide | HCID 21250756 | — |
| Product | 2-Hydroxy-4-methylbenzamide | HCID 10534839 | — |
Reaction Steps
The starting-material, 4-methyl-2-propoxybenzamide, was prepared by reacting methyl 4-methyl-salicylate (25.75 g) with ethanolic ammonia to yield 4-methylsalicylamide (12.54 g) which was then reacted with bromopropane, potassium iodide and potassium carbonate in acetone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06200980B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-7460a491c17d4446ac2dd6b649dbeeb0 |
| Source note | uspto-grants-2001_03 |