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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1532103Generated: November 2, 2026

1-Methylpiperazine → 1-Methyl-5-[5-(4-methyl-1-piperazinylmethyl)-2-n-propoxyphenyl)-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-pyrimidin-7-one

https://huagongshe.com/reaction/1532103

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
Reactant5-(5-Chloromethyl-2-n-propoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo-[4,3-d]pyrimidin-7-oneHCID 136116209—
Product1-Methyl-5-[5-(4-methyl-1-piperazinylmethyl)-2-n-propoxyphenyl)-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-pyrimidin-7-oneHCID 136331510—

Reaction Steps

The title compound was prepared from 5-(5-chloromethyl-2-n-propoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one and 1-methylpiperazine, following the procedure of Example 84, and was obtained as a colourless solid (36%), m.p. 149-150° C. Found: C,65.68; H,7.33; N,19.10. C24H34N6O2 requires C,65.73; H,7.81; N,19.16%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06200980B1
Source datasetuspto-grants-2001_03
ORD IDord-2f8129a70ad7403bae1f36812cce653e
Source noteuspto-grants-2001_03