Sulfuryl chloride → HCID 21250803, compound

Participants

Reaction Steps

A solution of 1-benzylpiperazine (20.0 g, 0.114 mol) in acetonitrile (45 ml) was added to a solution of sulphuryl chloride (28 ml, 0.346 mol) in acetonitrile (50 ml) and the mixture heated under reflux for 17 hours, then cooled. The solvent was removed by evaporation under vacuum, then the residue triturated with either (20×50 ml) to yield the title compound (27.8 g, 89%), which was used without further purification.

Provenance & Evidence