Toluene → HCID 54465775, compound

HRID 1532279Notes

Reaction equation

HRID 1532279 reaction equation
[CH2:1]([O:3][C:4](=[O:20])[C:5]1[CH:10]=[C:9]([Cl:11])[C:8]([S:12]([CH2:15]C(O)=O)(=[O:14])=[O:13])=[C:7]([Cl:19])[CH:6]=1)[CH3:2].C1(C)C=CC=CC=1>N1C=CC=CC=1>[CH2:1]([O:3][C:4](=[O:20])[C:5]1[CH:6]=[C:7]([Cl:19])[C:8]([S:12]([CH3:15])(=[O:14])=[O:13])=[C:9]([Cl:11])[CH:10]=1)[CH3:2]

Participants

4

Reactant 2

HCID 1140TolueneHCID 54239701HCID 54239701, compound

Product 1

HCID 54465775HCID 54465775, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

3,5-Dichloro-4-[(carboxymethyl)sulfonyl]benzoic acid ethyl ester (3.1 g) was mixed with toluene (100 mL) and pyridine (1.0 mL) and the mixture was refluxed for 30 min and then evaporated to dryness (yield 2.6 g). 1H-NMR (400 MHz, DMSO-d6) d=1.34 (t, J=7.0 Hz, 3H), 3.51 (s, 3H), 4.37 (q, J=7.0 Hz, 2H), 8.05 (s, 2H).

Workup

  1. temperaturethe mixture was refluxed for 30 min
  2. customevaporated to dryness (yield 2.6 g)

Sources & evidence

ORD record
ord-6cb2b2cc82f2452f8c0072ddb225d91e
Source dataset
uspto-grants-2001_03
Patent number
US06201027B1

Reaction notes

Loading…