HCID 53995284, compound → 3,5-Dichloro-4-(methylsulfonyl)benzaldehyde

HRID 1532281Notes

Reaction equation

HRID 1532281 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([Cl:14])[C:9]=1[S:10]([CH3:13])(=[O:12])=[O:11])[CH2:5][OH:6]>ClCCl.[O-2].[Mn+4].[O-2]>[Cl:14][C:8]1[CH:7]=[C:4]([CH:3]=[C:2]([Cl:1])[C:9]=1[S:10]([CH3:13])(=[O:12])=[O:11])[CH:5]=[O:6]

Participants

4

Reactant 1

HCID 53995284HCID 53995284, compound

Product 1

HCID 212517313,5-Dichloro-4-(methylsulfonyl)benzaldehyde

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 6344DichloromethaneSolvent

Conditions

Temperature
25 °C

Procedure

3,5-Dichloro-4-(methylsulfonyl)benzyl alcohol (1.7 g) was dissolved in dichloromethane (35 mL) and then active manganese(IV) oxide (7.0 g) was added and the mixture was stirred for 25 min at 22-28° C. The solid was removed by filtration and the filtrate was evaporated to dryness (yield 1.5 g). 1H-NMR (400 MHz, DMSO-d6 d=3.53 (s, 3H), 8.12 (s, 2H), 10.02 (s, 1H).

Workup

  1. customThe solid was removed by filtration
  2. customthe filtrate was evaporated to dryness (yield 1.5 g)

Sources & evidence

ORD record
ord-bf8442da750440839a8c806772aa8485
Source dataset
uspto-grants-2001_03
Patent number
US06201027B1

Reaction notes

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