Pyridine → HCID 70225066, compound

Participants

Reaction Steps

To a solution of pyridine from Step 5 above (3.74 g, 5.66 mmol) in a CH2Cl2 MeOH mixture (180 mL/18 mL) was added 4.2 g (8.55 mmol) of MMPP in one portion. The resulting solution was stirred at room temperature for 5 h and purified directly by flash chromatography on silica gel (Gradient 100% CH2Cl2to 5% MeOH/CH2Cl2 to 5% (10% NH4OH/MeOH)/CH2Cl2) to afford 4 g of contaminated carbamate pyridine-N-oxide.

Provenance & Evidence