HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1532534Generated: October 31, 2026
Hydrochloric Acid → 4-Ethynyl-4,4'-dipentylbicyclohexyl
https://huagongshe.com/reaction/1532534
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 4-(1,2-Dibromoethyl)-4,4'-dipentylbicyclohexyl | HCID 15456825 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Solvent | tert-Butanol | HCID 6386 | — |
| Product | 4-Ethynyl-4,4'-dipentylbicyclohexyl | HCID 15451976 | — |
Reaction Steps
32.48 g of KOtBu are added at RT to 47.50 g of 4-(1,2-dibromoethyl)-4,4′-dipentylbicyclohexyl in 150 ml of tert-butanol. The mixture is heated to 60° C. and stirred at this temperature overnight. Water is subsequently added to the reaction mixture, which is acidified with dilute hydrochloric acid and subjected to conventional work-up, giving 4-ethynyl-4,4′-dipentylbicyclohexyl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06203724B1 |
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| Source dataset | uspto-grants-2001_03 |
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| ORD ID | ord-7741f9bc30f3400cbec45fdcd9a0be6d |
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| Source note | uspto-grants-2001_03 |
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