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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1532546Generated: October 31, 2026

2,5-Dichlorotoluene → Methyl 5-(2,5-Dichlorophenyl)pentanoate

https://huagongshe.com/reaction/1532546

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-DichlorotolueneHCID 29572—
ReactantTrimethyl 4-bromoorthobutyrateHCID 5187924—
ProductMethyl 5-(2,5-Dichlorophenyl)pentanoateHCID 22013526—

Reaction Steps

The anion of 2,5-dichlorotoluene was reacted with trimethyl 4-bromoorthobutyrate to produce methyl 5-(2,5-dichlorophenyl)pentanoate after hydrolytic work-up. Competitor 11 was prepared by LiOH hydrolysis of the methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06204005B1
Source datasetuspto-grants-2001_03
ORD IDord-fc44d69ce2bb473996db1f7306a4ab78
Source noteuspto-grants-2001_03