Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Ethyl 2-chloro-3-(2-chloro-5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)phenyl)-2-propenoate | HCID 3525006 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 54280578 | HCID 54280578 | — |
Reaction Steps
1.39 ml of a 40% strength by weight aqueous dimethylamine solution were added to a solution of 3.9 g of N-[4-chloro-3-(2-chloro-2-ethoxycarbonylethenyl)phenyl]-3,4,5,6-tetrahydrophthalimide in 100 ml of acetonitrile at about 20° C. The mixture obtained was stirred for a further 20 hours at 20-25° C., after which the solid formed was separated off, washed with petroleum ether and finally dried. Mp.: 161-164° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06204222B1 |
|---|
| Source dataset | uspto-grants-2001_03 |
|---|
| ORD ID | ord-c587040151564a01ac01f9e4ea2bd8f5 |
|---|
| Source note | uspto-grants-2001_03 |
|---|
