HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → HCID 22386596, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2,4-Quinazolinediamine, 5-fluoro- | HCID 456246 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 22386596 | HCID 22386596 | 4.8% |
Reaction Steps
Aniline (5.0 g, 50 mmol, Aldrich), sodium hydride (1.5 g, 50 mmol of an 80% dispersion in mineral oil) and 2,4-diamino-5-fluoroquinazoline (4.4 g, 25 mmol) in 80 mL of dimethyl sulfoxide were reacted as in Procedure A to give 0.3 g (4.8% yield) of 2,4-diamino-5-anilinoquinazoline, m.p. 279-283° C. (dec).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06204267B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-110ac2d12b9343058d6b9fd74d47a7de |
| Source note | uspto-grants-2001_03 |