Hydrochloric Acid → HCID 22013934, compound

Participants

Reaction Conditions

Reaction Steps

Combine o-phenylenediamine (10.8 g, 100 mmol) and d,l-alanine (13.4 g, 150 mmol) in 6 N HCl (100 mL) Heat at reflux 75 hours, allow to cool, and chill at −15° C. Filter to remove 2.4 g solid. Decolorize the filtrate with charcoal, concentrate in vacuo to 30 g, and dilute with 95% EtOH (90 mL). Chill at −15° C., filter and wash with cold 90% EtOH to obtain the title compound as a white powder.

Provenance & Evidence