Hydrochloric Acid → HCID 22013937, compound

Participants

Reaction Conditions

Reaction Steps

Combine o-phenylenediamine (10.8 g, 100 mmol) and sarcosine (13.4 g, 150 mmol) in 6 N HCl (100 mL). Heat at reflux 90 hours, allow to cool, and concentrate in vacuo to 45 g. Add EtOH (50 mL) and chill at −15° C. Filter the solid and wash with cold 90% EtOH. Dissolve in 80% EtOH (150 mL) and decolorize with charcoal. Concentrate in vacuo to 28 g, warm with 95% EtOH (160 mL), allow to cool, and filter to provide colorless rods.

Provenance & Evidence