1-Chloro-2-nitrobenzene → N~1~,N~1~-Dimethyl-N~3~-(2-nitrophenyl)propane-1,3-diamine

Participants

Reaction Conditions

Reaction Steps

N,N-Dimethyl-1,3-propanediamine (3.24 g) was added to a solution containing 2-chloronitrobenzene (2.00 g) in pyridine (2.56 ml). After being stirred for 13 hours at 120-130° C., the reaction mixture was concentrated. The residue, with toluene added thereto, was washed with saturated sodium hydrogencarbonate aqueous solution and saturated brine successively, dried over sodium sulfate anhydride, and concentrated, thereby yielding the entitled compound (2.83 g) as orange oil.

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