Hydrogen chloride-ethyl acetate → HCID 22013781, compound

Participants

Reaction Steps

4N Hydrochloric acid/ethyl acetate solution (0.68 ml) was added to a solution containing 1-[2-(dimethylamino)ethyl]-2-henicosyl-N-methyl-1H-benzimidazole-5-carboxamide (1.345 g) in a mixture of ethyl acetate (14 ml) and ethanol (1.5 ml). After being stirred for 30 minutes while being cooled with ice, the reaction mixture was concentrated. The residue was recrystallized with the mixed solution of ethyl acetate-ethanol, thereby yielding the entitled compound (1.254 g) as white crystals.

Provenance & Evidence