(+-)-2-Butanol → HCID 22014126, compound

Participants

Reaction Steps

The product from Example 1308C (420 mg, 3.0 mmol) in DMF (3.0 mL), 2-butanol (1.1 mL, 12.0 mmol) in DMF (6.0 mL) and NaH, 60% dispersion in mineral oil, (240 mg, 6.0 mmol) in DMF (12 mL) were allowed to react in a manner similar to that described in Example 1308D. The residue was chromatographed (silica gel; EtOAc/hexanes, 1:12) to afford a clear oil (355 mg, 55%). MS (CI/NH3) m/z: (M+NH4)+ 232.

Provenance & Evidence