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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 15330Erstellt: 25. Oktober 2026

Water → Furo[2,3-c]pyridin-5-ylmethanol

https://huagongshe.com/reaction/15330

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktWaterHCID 962—
EduktSodium HydroxideHCID 14798—
EduktHCID 22047292HCID 22047292—
Lösungsmittel1,4-DioxaneHCID 31275—
ProduktFuro[2,3-c]pyridin-5-ylmethanolHCID 2204717470,4%

Reaktionsschritte

Also to yield the desired compound: Furo[2,3-c]pyridin-5-ylmethyl acetate (1.15 g, 6 mmol) was dissolved in 1,4-dioxane (30 ml) and water (10 ml) and treated with 2N sodium hydroxide solution (12 ml) and stirred at RT for 18 h. The mixture was then partitioned between ethyl acetate and water, the organic layer was dried and evaporated to dryness to provide the desired compound (0.63 g).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07732461B2
Quelldatensatzuspto-grants-2010_06
ORD IDord-adde202e72824f69a5298fe6bf9019ec
Quellennotizuspto-grants-2010_06