HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 1-benzothiophene-3-carboxylate → 1-Benzothiophen-3-ylmethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 1-benzothiophene-3-carboxylate | HCID 12514024 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-Benzothiophen-3-ylmethanol | HCID 2776342 | 105.4% |
Reaction Steps
An ether solution (50 ml) of methyl benzo[b]thiophene-3-carboxylate (15 g) was added dropwise to a suspension of lithium aluminium hydride (3.5 g) in ether (100 ml) followed by reflux for 2 h. Usual work-up gave benzo[b]thiophen-3-yl methanol (13.5 g) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06207677B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-35b58d3c1c0b4da8b130dd1abc315efb |
| Source note | uspto-grants-2001_03 |