Furo[2,3-c]pyridin-5-ylmethanol → HCID 57423121, compound

HRID 15331Notes

Reaction equation

HRID 15331 reaction equation
[O:1]1[C:5]2=[CH:6][N:7]=[C:8]([CH2:10][OH:11])[CH:9]=[C:4]2[CH:3]=[CH:2]1>C(O)C.[H][H].[Pd]>[O:1]1[C:5]2=[CH:6][N:7]=[C:8]([CH2:10][OH:11])[CH:9]=[C:4]2[CH2:3][CH2:2]1

Participants

5

Reactant 1

HCID 22047174Furo[2,3-c]pyridin-5-ylmethanol

Product 1

HCID 57423121HCID 57423121, compoundYield 100%

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 702EthanolSolventHCID 178418361HCID 178418361, compoundSolvent

Procedure

Furo[2,3-c]pyridin-5-ylmethanol (1.29 g, 8.7 mmol) was dissolved in ethanol (50 ml) and hydrogenated under 1 atmosphere of hydrogen at room temperature over 10% palladium on carbon for 18 h. The mixture was filtered and the filtrate evaporated to dryness to provide the desired compound (1.31 g, 100%).

Workup

  1. filtrationThe mixture was filtered
  2. customthe filtrate evaporated to dryness

Sources & evidence

ORD record
ord-36cdf0e899e84abf95e5f5cb6067358e
Source dataset
uspto-grants-2010_06
Patent number
US07732461B2

Reaction notes

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