Isocyanate → HCID 22707710, compound

HRID 1533134Notes

Reaction equation

HRID 1533134 reaction equation
C[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[C:4]([N:12]1[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]1)=[N:5][CH:6]=[N:7]2.[N-:18]=[C:19]=O.[N-:21]=[C:22]=[S:23]>>[N:18]1[CH:19]=[CH:11][CH:2]=[C:3]([CH2:8][NH:21][C:22]([N:15]2[CH2:14][CH2:13][N:12]([C:4]3[C:3]4[C:8](=[CH:9][CH:10]=[CH:11][CH:2]=4)[N:7]=[CH:6][N:5]=3)[CH2:17][CH2:16]2)=[S:23])[CH:4]=1

Participants

4

Reactant 3

HCID 105034IsocyanateHCID 22707673HCID 22707673, compoundHCID 178418790HCID 178418790, compound

Product 1

HCID 22707710HCID 22707710, compound

Procedure

In the following Examples 287 and 288, substantially the same procedure as in Example 1 was repeated, except that 5-methyl-4-(1-piperazinyl)quinazoline was used in place of 6,7-dimethoxy-4-(1-piperazinyl)quinazoline, and the corresponding isocyanate or isothiocyanate was used in place of phenyl isocyanate, to give the desired compound.

Sources & evidence

ORD record
ord-4653654dd8d7419ba51325dab93f9bf9
Source dataset
uspto-grants-2001_03
Patent number
US06207667B1

Reaction notes

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