反应详情

2,3-Dihydrofuro[2,3-c]pyridin-5-ylmethanol (1.31 g, 8.7 mmol) was dissolved in dichloromethane (100 ml) and treated with manganese dioxide (6 g, 69 mmol) at ambient temperature with vigorous stirring for 18 h. The mixture was filtered through kieselguhr and the filtrate evaporated to dryness to provide the desired compound (0.9 g, 70%).

1. filtrationThe mixture was filtered through kieselguhr
2. customthe filtrate evaporated to dryness