Salicylaldehyde → Methyl 3-(2-hydroxyphenyl)prop-2-enoate

Participants

Reaction Steps

To a solution of 2-hydroxybenzaldehyde (2.44 g) in toluene (25 ml) was added methoxycarbonylmethylene-triphenylphosphorane (6.68 g) and the mixture was stirred for 3 hours at ambient temperature. The mixture was filtered and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography [eluting with ethyl acetate - n-hexane (1:1)] to give methyl 3-(2-hydroxyphenyl)acrylate (2.47 g).

Provenance & Evidence