2,4-Dichlorophenylacetic acid → 2-[(2,4-Dichlorophenyl)acetamido]butyric acid isobutyl ester

HRID 1533550Notes

Reaction equation

HRID 1533550 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10]([OH:12])=O.[NH2:13][CH:14]([CH2:22][CH3:23])[C:15]([O:17][CH2:18][CH:19]([CH3:21])[CH3:20])=[O:16]>>[CH2:18]([O:17][C:15](=[O:16])[CH:14]([NH:13][C:10](=[O:12])[CH2:9][C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[Cl:1])[CH2:22][CH3:23])[CH:19]([CH3:20])[CH3:21]

Participants

3

Reactant 2

HCID 882092,4-Dichlorophenylacetic acidHCID 13743360Isobutyl 2-aminobutyrate

Product 1

HCID 541261332-[(2,4-Dichlorophenyl)acetamido]butyric acid isobutyl ester

Procedure

Following General Procedure I′ above and using 2,4-dichlorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-273150ccf622419b89218145de19c2bd
Source dataset
uspto-grants-2001_03
Patent number
US06207710B1

Reaction notes

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