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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1533557Generated: November 3, 2026

3-(Trifluoromethyl)benzeneacetic acid → 2-[(3-trifluoromethylphenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/1533557

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)benzeneacetic acidHCID 67695—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(3-trifluoromethylphenyl)acetamido]butyric Acid Iso-butyl EsterHCID 15481772—

Reaction Steps

Following General Procedure I′ above and using 3-trifluoromethylphenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06207710B1
Source datasetuspto-grants-2001_03
ORD IDord-58f4fb9f5fe0400ca772791e3091888d
Source noteuspto-grants-2001_03