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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1533570Generated: November 1, 2026

3-Thiophenacetic acid → N-[(3thienyl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/1533570

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Thiophenacetic acidHCID 23404—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3thienyl)acetyl]alanine Iso-butyl EsterHCID 53969374—

Reaction Steps

Following General Procedure I′ above, and using 3-thiopheneacetic acid (Aldrich) and alanine iso-butyl ester (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06207710B1
Source datasetuspto-grants-2001_03
ORD IDord-be37c689ba304240877e5ee3afd5ffd2
Source noteuspto-grants-2001_03