Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1533691Generated: November 5, 2026

(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acid → HCID 22894865, compound

https://huagongshe.com/reaction/1533691

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acidHCID 12135350—
ReactantHCID 22492205HCID 22492205—
ProductHCID 22894865HCID 22894865—

Reaction Steps

Following General Procedure C and using N-(3,5-difluorophenylacetyl)-L-alanine (from Example B2 above) and methyl 2-amino-2-(6-aminopyrid-2-yl)acetate (prepared from 2-(methoxyimino)-2-(6-aminopyrid-2-yl)acetic acid [CAS 71470-33-2] using General Procedures G and AC above), the title compound was prepared. The product was purified by LC 2000 preparative column chromatography using 1:1 EtOAc/hexanes as the eluent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06207710B1
Source datasetuspto-grants-2001_03
ORD IDord-79e85c5759e948668ecef96c30ccd86a
Source noteuspto-grants-2001_03